Sartorius Biostat RM Bioreactor System
The Biostat RM (Rocking Motion), is a fully GMP compliant, wave-mixed bioreactor. It is used with single-use Flexsafe RM bags which are proven for a broad range of different cell lines incl. CHO, NS0, SF9, E.coli, stem cells and CAR-T cells. Depending on your individual process needs and working volumes you can choose from a variety of system and bag configurations.
Biostat RM is a perfectly sized, single-use, wave-mixed benchtop bioreactor for stand-alone use. It features an exchangeable bag holder to fit bags with a total volume of 1 – 20 L. The Biostat RM Basic rocking platform with an integrated local controller, Air/CO2 mixing module is the optimal choice for straight-forward applications, such as seed generation.The Biostat B is a universal benchtop controller for stirred and rocking motion systems. It combines with the RM Rocker for advanced process control featuring pH, DO and BioPAT Viamass. The system is fully configurable and can therefore serve various process needs, from process development to small scale commercial production.
The wave generated in the RM bags due to the rocking motion ensures effective gas exchange through the gas-liquid interface. Four different gas lines for air, O2, N2 and CO2 are equipped with flow meters and four high-precision mass flow controllers. An integrated pressure sensor continuously measures the pressure inside the bag. To ensure process safety, aeration is switched off when an upper threshold is reached.
Total volume: up to 20LMinimum working volume: 0.1LMaximum working volume: 10LTemperature range: Room temperature to 40°CMaximum total gas flow: 0 – 1000 ml/min, or 2x 0 – 500 ml/minFixed CO2 gassing: 0 – 15 %Rocker speed: 8 – 42 rpmRocker angle: 4 -10°Dimensions (WxHxD): 765 x 600 x 400 mmWeight: 30 kg